Arsenic Represses Myogenesis and Neurogenesis through Epigenetic Mechanisms, Repressed Transcription Factors, and Altered Wnt Signaling Pathway
نویسندگان
چکیده
................................................................................................. 36 Introduction ............................................................................................ 38 Methods.................................................................................................. 41 Results .................................................................................................... 44 Discussion .............................................................................................. 46 Acknowledgements ................................................................................ 51 References .............................................................................................. 52 Table ....................................................................................................... 58 Figures .................................................................................................... 59 III. SODIUM ARSENITE REPRESSES THE EXPRESSION OF MYOGENIN IN C2C12 MOUSE MYOBLAST CELLS THROUGH HISTONE MODIFICATIONS AND ALTERED EXPRESSION OF EZH2 AND IGF-1 .................................................................................. 64 Abstract ................................................................................................. 65 Introduction ............................................................................................ 67 Methods.................................................................................................. 70................................................................................................ 65 Introduction ............................................................................................ 67 Methods.................................................................................................. 70
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Arsenic exposure inhibits myogenesis and neurogenesis in P19 stem cells through repression of the β-catenin signaling pathway.
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